The underlying immune mechanisms of allergic occupational asthma correspond to type i allergy ie antigen recognition and processing by antigen presenting cells induction of the th2 immune response resulting in the production of antigen specific ige antibodies and finally release and generation of bronchospastic and inflammatory mediators . Recent developments in occupational asthma research and clinical practice are the focus of this publication it discusses the contribution of occupational exposures to chemical and biological agents to the burden of asthma in adults powerful approaches like the use of apprentices studies which progress in inflammation research free . With occupational asthma lung inflammation may be triggered by an allergic response to a substance which usually develops over time alternatively inhaling fumes from a lung irritant such as chlorine can trigger immediate asthma symptoms in the absence of allergy. A cup of health with cdc occupational asthma asthma mortality study asthma asthma attacks and emergency department visits indoor environmental quality asthma research learn about the research niosh is conducting on work related asthma page last reviewed may 11 2017. Recent developments in the field of occupational asthma research and clinical practice are the topic of this volume the contribution of occupational exposures to chemical and biological agents to the burden of asthma in adults is clearly described in an overview of the most recent epidemiological data from both general population and industry based studies
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