2 an introduction to feedback control in systems biology control theory ofocuses on the essential ideas and concepts from control theory that have found applicability in the systems biology research literature including basic linear introductory material but also more advanced nonlinear techniques. Feedback control in systems biology 1 boca raton london new york crc press is an imprint of the taylor francis group an informa businessc 2012 by taylor francis group llck10870 fmindd 1 9 7 11 427 pm. Like engineering systems biological systems must also operate effectively in the presence of internal and external uncertainty such as genetic mutations or temperature changes for example it is not surprising then that evolution has resulted in the widespread use of feedback and research in systems biology over the past decade has shown that
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